This poster, presented at USHUPO from Prognomiq describes how Seer’s Proteograph™ nanoparticle technology specifically captures unique proteoforms in the corona formation and allow for comprehensive assessment of the circulating glycoproteome.
This study examines in detail the relationship between the unique physicochemical properties of a panel of proprietary engineered nanoparticles (NPs) and the diverse pattern of protein sampling that is enabled by a unique nano-bio interface that is created between a given NP surface and a given biological sample.
This poster, presented at USHUPO describes a performance evaluation between label-free and tandem mass tag multiplex methods for plasma proteomics. The Proteograph Product Suite enables rapid, automated and reproducible sample prep for larger sample cohorts.
This poster demonstrates a DIA-NN approach combined with the cloud-based large group run more sensitively identifies protein groups across the cohort (~4000 vs the previous ~2,500), enabling development of improved classification models and marker discovery.
Presented at USHUPO 2022, this study describes how nano-bio interactions may be tuned to optimize the binding and capture of a large and diverse set of proteins, including cytokines and hormone signaling proteins.
This poster, presented at USHUPO 2022 describes a comparison of performance between label-free Data Dependent Acquisition (DDA) and TMT multiplexing methods with a set of control plasma samples processed with Proteograph Product Suite for deep plasma proteomic analysis.
This article demonstrates the utility of combined unbiased proteomics with transcriptomic analysis, and identified over 400 subject-specific protein variants, showing how the Proteograph Product Suite can support proteogenomics studies.