Seer Technology Access Center

Your premier, full-service partner for deep, unbiased proteomic insights

Seer’s white-glove service programs are designed to extend the scope of your research, get results faster, and pursue answers to critical biology. Get a customized quote today.

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Multi-omics and Proteomics Researchers

who would like to run a biological study to understand the benefits of deep, unbiased proteomic data for discovery.

Mass Spectrometry Researchers

who would like to better understand the Proteograph performance and nanoparticle enrichment power on their own LC-MS systems.

New Seer Customers

who need LC-MS services and support for a period of time.

Expanding the boundaries of biological discovery together

Comprehensive features of Seer Technology Access Center projects:

Dedicated project management and coordination team
Industry-leading turnaround times without sacrificing depth of insights
Optimized LC-MS workflows for global proteome discovery
Direct analysis of biosamples without extensive sample manipulations which can compromise complete characterization of the proteome
Detailed reports with interactive data visualizations in Proteograph Analysis Suite (PAS)
Direct access to raw MS files, and protein/peptide quantification tables

We make it easy to undertake studies of significance

STAC Program Title	Description	Study Size	Sample Types	Data Analysis	Proteograph Product Suite
Proof of Principle (POP)	Full POP – Sample to data analysis and insights in 3-weeks Partial POP – Sample to MS-ready peptides in 2-weeks; LC-MS run and services not included	Up to 20 samples	Species agnostic: Plasma or Serum Cerebrospinal Fluid (CSF) Secretome (i.e. conditioned media from cell lines or organoids) Host Cell Proteins in biologics	Detailed standard report 3-month trial access to the Proteograph Analysis Suite for browsing results and interpretation	Proteograph purchase not included Rebate towards Proteograph purchase
Standard Service Projects	Full service from biofluid to LC-MS data, and analysis with key insights.	21 to 500 samples	Species agnostic: Plasma Cerebrospinal Fluid (CSF) Secretome (i.e. conditioned media from cell lines or organoids) Host Cell Proteins in biologics	Detailed standard report Initial 60-minute project consultation Dedicated 10 hours of data analysis assistance	Proteograph purchase not included No rebate
Proteograph XTM Services	Managed LC-MS run and services on Proteograph Samples prepared by customers Average timing is 3-6 weeks	Enables 1000s of samples	Species agnostic: Plasma or Serum Cerebrospinal Fluid (CSF) Secretome (i.e. conditioned media from cell lines or organoids) Host Cell Proteins in biologics	Detailed standard report Initial 60-minute project consultation Dedicated 10-hours of data analysis assistance	For Proteograph customers only

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Push the boundaries of biological discovery with Proteograph XT and Thermo Scientific Orbitrap Astral Mass Spectrometry

More proteins, more data, more insights

6,000 protein groups identified and quantified at the amino acid level
54,000+ unique peptides including multiple measurement points per protein
Representative data from <1-hour of control pooled healthy human plasma on Orbitrap Astral MS

Sensitive, accurate, and reproducible insights.

>8 Orders of Magnitude of protein concentrations measured in Plasma
Protein coefficients of variation of less than 11% with Proteograph XT Assay
In <1-hour reproducible coverage across entire HPPP dynamic range

STAC offers the latest LC-MS technologies

Sample-to-Sample Analysis Time

30 min DIA
60 min DDA

Liquid Chromatography (LC)

Vanquish Neo or Ultimate 3000 Pharmafluidics µPAC (50cm C18)

Injection Mass

400 ng

Sample-to-Sample Analysis Time

30 min DIA
60 min DDA

Liquid Chromatography (LC)

Vanquish Neo or Ultimate 3000 Pharmafluidics µPAC (50cm C18)

Injection Mass

480 ng

Sample-to-Sample Analysis Time

60 min DDA

Liquid Chromatography (LC)

Vanquish Neo or Ultimate 3000 Pharmafluidics µPAC (50cm C18)

Injection Mass

480 ng

Sample-to-Sample Analysis Time

30 min DIA
60 min DDA

Liquid Chromatography (LC)

Ultimate 3000 Pharmafluidics µPAC (50cm C18)

Injection Mass

200 ng

Sample-to-Sample Analysis Time

30 min DIA
(No DDA option)

Liquid Chromatography (LC)

ACQUITY UPLC M-Class Pharmafluidics µPAC (50cm C18)

Injection Mass

400 ng

Why customers are choosing Seer

The combination of Proteograph XT and Orbitrap Astral in my longitudinal plasma sample of astronauts across two missions, pre-flight and post-flight, resulted in **identification of over 7,500 proteins**, forming the basis **for identification of new biomarkers** that change after spaceflight. I am thrilled with the performance of Seer’s proteomic platform and my collaboration with the Seer investigators and look forward to continued profiling for future missions.
**Christopher Mason, PhD**LinkedIn

Proteograph Resources

Paper

Differential BMP1 Isoform Levels in Plasma: Contrasting Patterns between NSCLC Patients and Healthy Controls

In Donovan et al.'s study, peptide-level data is emphasized for its enhanced resolution over protein-level insights, leading to improved identification of differentially abundant peptides in non-small cell lung cancer (NSCLC) subjects compared to controls.

App Note

Accelerating throughput with the Proteograph^™ XT Assay

Seer's Proteograph XT Assay enables large-scale cohort studies with optimal coverage, depth, and reproducibility, identifying over 5,000 plasma proteins in nearly 1,800 samples, and completing the entire workflow on approximately 1,800 samples in around 11 weeks, offering a faster route to gain deeper biological insights through expedited proteomics analysis.

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Poster

Large-scale, deep plasma proteomics: An 1800 sample study of Alzheimer’s disease

This poster demonstrates scaling a proteomics study of Alzheimer’s disease (AD) cohort using a new, high-throughput Proteograph™ XT Assay in development enables powerful insights into AD biology. (>5000 protein group IDs across a ~1800 subject AD cohort study.)

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Paper

Enhancing pQTL analysis with Proteograph™ Product Suite: A comparative study on MS-based and affinity-based proteomics methods

Utilizing the Proteograph™ Product Suite for pQTL analysis, Karsten Suhre, Ph.D. introduces a novel MS-based method, detecting over 3,000 proteins from 345 individuals, and demonstrates higher precision and clinically relevant insights compared to traditional affinity-based methods.

Keep Exploring

Proteograph Product Suite

With Seer’s new Proteograph XT, your view of the proteome expands. Your lab’s workflow gains momentum. You can look for answers in every dimension, and push science forward every day.

Learn More

Proteomics Video Gallery

Visit Seer’s proteomics video gallery. Watch technology overviews, scientific presentations, customer stories, and more.

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On-Demand Webinar, Deep Proteomic Insights Across Human Biofluids

Evotec demonstrates the exceptional power of the Proteograph workflow in a human biofluids benchmark study. View webinar today.

Watch Now

Trademarks

Thermo Scientific, OrbiTrap, Astral, Lumos, Exploris, Bruker, Sciex, are trademarks of their respective owners. All other trademarks are the property of their respective owners.