Dedicated project management
and coordination team provides fully managed service for Seer enrichment, MS and data analysis in 3-6 weeks
STAC (Seer Technology Access Center)
Seer’s white-glove service includes sample processing, mass spectrometry (MS), and data analysis from end to end. Customers simply collect and ship their samples. No internal instrument, lab, or MS needed.
Key benefits
Detailed reports
with interactive data visualizations in Proteograph Analysis Suite (PAS) and access to raw MS files and quantification results
The latest LC-MS technology and capabilities
including state-of-the art instrumentation from leading commercial vendors like Thermo Fisher Scientific, Bruker, and Sciex
Optimized LC-MS workflows
for global proteome discovery and unparalleled insights
STAC projects enable proteomics that accelerates time to answers
Biomarker discovery
Find disease/response signatures in plasma
Target ID/validation
Prioritize targets tied to phenotype
Patient stratification
Identify responder vs non-responder proteotypes
Safety/tox signals
Detect off-target biology early
Mechanism of action (MoA)
Reveal pathway shifts under treatment
Multi-omics integration
Combine proteomics with genomics + clinical data
Unlock high-impact biological insights at scale
- Discover biomarkers in large clinical cohorts
- Enable patient stratification and hypothesis generation from real-world samples
- Support target discovery & prioritization from protein-level biology
- Generate data designed for downstream modeling + multi-omics integration
Example of research studies supported by STAC
- Which circulating proteins predict progression or relapse?
- What protein signatures separate responders vs non-responders?
- Which pathways shift post-dose in humans?
From samples to decisions: proteomics designed for translational programs
Flowchart: Cohort/samples → Proteograph workflow → Deep proteomic profiles → Biological insights → Decision support. Outputs: Biomarker candidates, MoA/pathway readouts, and stratification models.
STAC combines Proteograph sample preparation, high-throughput MS, and analysis workflows to deliver reproducible proteomic readouts that support biomarker, MoA, and patient stratification studies.
What you get:
Quantitative proteome coverage
suited for complex clinical matrices
Reproducible cohort-scale measurements
ready for statistics/ML
Actionable outputs
for discovery → validation → translational decisions
STAC delivers outputs built for translational workflows
What you get:
Structured deliverables
for rapid internal decision-making
Cohort-level QC reporting
to support confidence and reproducibility
Comparative analyses
aligned to your study questions (disease vs control,
pre/post treatment, responder vs non-responder)
Data formats compatible
with downstream modeling and interpretation
Collaborative study support
from STAC scientists to reduce iteration cycles
We make it easy to undertake studies of significance
| STAC PROGRAM TITLE | DESCRIPTION | study size | sample types | data analysis | proteograph product suite |
|---|---|---|---|---|---|
| Standard Service Projects | Full service from biofluid to LC-MS data, and analysis with key insights |
21 to 500 samples |
Species agnostic:
|
Detailed standard report Initial 60-minute project consultation Dedicated 10 hours of data analysis assistance |
Proteograph purchase not included No rebate |
| Proteograph Mass Spec Services | Managed LC-MS run and services on Proteograph Samples prepared by customers Average timing is 3-6 weeks |
Enables 1000s of samples |
Species agnostic:
|
Detailed standard report Initial 60-minute project consultation Dedicated 10 hours of data analysis assistance |
For Proteograph customers only |
STAC PROGRAM TITLE
Standard Service Projects
DESCRIPTION
Full service from biofluid to LC-MS data, and analysis with key insights
study size
21 to 500 samples
sample types
Species agnostic:
- Plasma
- Cerebrospinal Fluid (CSF)
Secretome (i.e. conditioned media from cell lines or organolds) - Host Cell Proteins in biologics
- And more
data analysis
Detailed standard report
Initial 60-minute project consultation
Dedicated 10 hours of data analysis assistance
proteograph product suite
Proteograph purchase not included
No rebate
STAC PROGRAM TITLE
Proteograph Mass Spec Services
DESCRIPTION
Managed LC-MS run and services on Proteograph
Samples prepared by customers
Average timing is 3-6 weeks
study size
Enables 1000s of samples
sample types
Species agnostic:
- Plasma or serum
Cerebrospinal Fluid (CSF)
Secretome (i.e. conditioned media from cell lines or organolds) - Host Cell Proteins in biologics
- And more
data analysis
Detailed standard report
Initial 60-minute project consultation
Dedicated 10 hours of data analysis assistance
proteograph product suite
For Proteograph customers only
STAC offers the latest LC-MS technologies
Sample–Sample Analysis Time
30 min DIA
60 min DDA
60 min DDA
Liquid Chromatography (LC)
Vanquish Neo or Ultimate 3000
Pharmafluidics µPAC (50cm C18)
Pharmafluidics µPAC (50cm C18)
Injection Mass
400 ng
Trademarks
Thermo Scientific, OrbiTrap, Astral, Vanquish, µPAC, nanoElute, ACQUITY, Bruker, Sciex, are trademarks of their respective owners. All other trademarks are the property of their respective owners.
Proteograph Resources
Paper
Differential BMP1 Isoform Levels in Plasma: Contrasting Patterns between NSCLC Patients and Healthy Controls
In Donovan et al.'s study, peptide-level data is emphasized for its enhanced resolution over protein-level insights, leading to improved identification of differentially abundant peptides in non-small cell lung cancer (NSCLC) subjects compared to controls.
App Note
Accelerating throughput with the Proteograph XT Assay
Seer's Proteograph XT Assay enables large-scale cohort studies with optimal coverage, depth, and reproducibility, identifying over 5,000 plasma proteins in nearly 1,800 samples, and completing the entire workflow on approximately 1,800 samples in around 11 weeks, offering a faster route to gain deeper biological insights through expedited proteomics analysis.
Poster
Large-scale, deep plasma proteomics: An 1800 sample study of Alzheimer’s disease
This poster demonstrates scaling a proteomics study of Alzheimer’s disease (AD) cohort using a new, high-throughput Proteograph XT Assay in development enables powerful insights into AD biology. (>5000 protein group IDs across a ~1800 subject AD cohort study.)
Paper
Enhancing pQTL analysis with Proteograph Product Suite: A comparative study on MS-based and affinity-based proteomics methods
Utilizing the Proteograph Product Suite for pQTL analysis, Karsten Suhre, Ph.D. introduces a novel MS-based method, detecting over 3,000 proteins from 345 individuals, and demonstrates higher precision and clinically relevant insights compared to traditional affinity-based methods.
Starting your proteomics research is effortless
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