Welcome to your help and resource hub for the Proteograph™ Product Suite

The presence of Host Cell Proteins (HCP) in biopharmaceuticals is of great concern owing to their potential to decrease therapeutic efficacy and mediate inappropriate immune responses. This application note describes how the Proteograph product suite can be successfully used for HCP analysis, delivering 4-6 times more identifications than other methods.

Ensure you are fully up to date with protocols for the Proteograph XT Assay, Peptide Quantification, and Peptide Reconstitution methods. A valuable reference for experienced users and essential reading if you are new to the assay.

Here you will find a series of training videos including all Proteograph XT Assay method steps from start to finish.

This poster demonstrates how multi-nanoparticle protein corona-based proteomics captures more proteins with accurate fold-changes, linearity, and precision compared to neat digestion plasma workflow.

This poster demonstrates how the Proteograph workflow performance, in combination with TMT 18-Plex, provides much deeper access to human plasma proteome (i.e., 3,094 proteins) and reveals insights into the inter-individual variation of response to the COVID-19 vaccination.

Biofluids are reservoirs of untapped knowledge that harbor a trove of protein biomarkers, yet complexities impede deep exploration. In this webinar for genomics and proteomics enthusiasts alike, Nate Basisty of the National Institute on Aging and Asim Siddiqui of Seer discussed the transformative power of cutting-edge, unbiased proteomics, harnessed by the Seer Proteograph workflow, and how it is reshaping the realms of aging and Alzheimer's disease (AD) research.