Proteograph ONE Assay
Unlock large-scale studies with the Proteograph ONE Assay
Proteograph® Product Suite
The Proteograph Product Suite puts you on the frontlines of discovery
Unlock the hidden insights of the proteome to spark new breakthroughs
The Proteograph ONE Assay brings the proteome into full view — delivering deep, reproducible, unbiased analysis for studies at scale.
› Identify up to 10X more protein groups than direct (neat) methods
› Analyze 1,000+ samples per week with the Proteograph ONE workflow
Leading experts choose Seer to help advance their research
I am super excited about the 2X boost in throughput we’ll achieve with the Proteograph ONE workflow, and the population scale studies it will enable.
Josh Coon, Ph.D.Professor of Chemistry and Biomolecular Chemistry
University of Wisconsin-Madison
Seer’s solution has always been unmatched in its depth and robustness—and now it’s further scalable and more cost-effective too. This allows us to assess the complexity of the proteome in our population studies at unprecedented resolution.
Gary Patti, Ph.D.Professor of Chemistry, Genetics and Medicine
Washington University
Proteograph ONE Workflow
With the Proteograph Product Suite, Seer enables you to uncover the insights that will elevate your advantage in proteomics—revealing more of the proteome for you, so you can unveil new discoveries for the world.
Proteograph ONE Assay
SP200 Automation Instrument
Optimize reproducibility and throughput with the SP200 Automation Instrument
Mass Spectrometry
Utilize mass spectrometry, the gold standard for high-resolution proteomic profiling
Proteograph Analysis Suite
Accelerate deep biological insights with the Proteograph Analysis Suite
Proteograph DIRECT Assay
Compared to a manual workflow, the Proteograph DIRECT assay delivers highly reproducible results for routine peptide preparation.
- Processes up to 80 cell or tissue homogenate samples for mass spectrometry analysis in a single 96-well plate
- Reduces hands-on time from 8 hours to 1 hour for 80 tissue homogenate samples
Proteograph Product Suite Technical Resources
Technical Note
Advancing Analytical Throughput and Depth in Plasma Proteomic Studies with the Proteograph ONE Workflow
Technical note
Automating Sample Preparation for Proteomic Analysis Using the Proteograph DIRECT Workflow
Specification Sheet
SP200 Automation Instrument Product Specifications
See why leading experts choose Seer to advance their research
Working with Seer has transformed our multi-omics biomarker discovery initiatives. Seer’s Proteograph is allowing us to generate unbiased, quantitative data for over 3000 pig plasma proteins, enabling us to find new biomarker signatures of slow-progressing diseases like CLN3 Batten Diseases in animal models.
John Brudvig, Ph.D. Assistant Professor of Pediatrics and Rare Diseases Group
Sanford Research LinkedIn
We asked Seer, could we use their nanoparticles… and to our great relief and surprise and happiness… it worked really well! So, we have exactly what we wanted… [and] if it works with GLP-1, it's going to work for a lot of other biological molecules like it… for lots and lots of different small hormones that we need to measure accurately. All of this is maturing right now… to this really quite magical, remarkable time.
Jennifer Van Eyk, Ph.D. Professor of Medicine and Biomedical Engineering, Director, Precision Biomarker Laboratories
Cedar-Sinai Cancer Institute LinkedIn
We are very excited to leverage Seer technology to enable deep and fast plasma proteome analysis. The ability to profile thousands of proteins in a discovery manner within an hour from plasma is unprecedented. This capability has redefined how we think about leveraging mass spectrometry on myriad clinical and translational projects.
Josh Coon, Ph.D. Professor of Chemistry and Biomolecular Chemistry
University of Wisconsin–Madison LinkedIn
Having unbiased access to the proteome with peptide-level insights is necessary to truly understand the proteome, its variants and its connection to human health and disease. Myself and my colleagues at WCM-Q were very satisfied that the Seer Proteograph technology was able to provide this.
Karsten Suhre, Ph.D. Professor of Physiology and Biophysics & Director of the Bioinformatics Core
Weill Cornell Medicine - Qatar LinkedIn
The Seer Proteograph platform uniquely combines deep, discovery-mode proteomic profiling of plasma and serum with the ability to feasibly scale studies for analysis of large cohorts. The technology allows us to perform statistically powered proteomic biomarker discovery campaigns directly in clinically accessible, yet complex and historically challenging, liquid biopsy specimen types.
Mark R. Flory, Ph.D. Senior Scientist, Cancer Early Detection Advanced Research Center (CEDAR), Knight Cancer Institute
Oregon Health and Science University LinkedIn
The Proteograph enables us to generate large-scale unbiased proteomic data at unparalled speed and depth of coverage. Our multi-omics studies combine unbiased genomics, transcriptomics and metabolomics with extensive proteomics data from the Proteograph to provide an unprecedented systems biology view of every subject. This comprehensive biological data enables us to develop transformative products for early disease detection in cancer and other complex diseases.
Bruce Wilcox, Ph.D. VP of Proteomics
PrognomiQ LinkedIn
Jumpstart your proteomic research
Seer enables unbiased, deep, rapid proteomics at scale through the Proteograph Product Suite in multiple ways to meet the budgetary and operational needs of all types of projects.
Contact us
Talk with our team of experts today to start expanding your lab’s capability for biological discovery.