Publications
Browse our recent publications
The utility of nanoparticle protein coronas for studying the plasma glycoproteome
This collaboration between Seer and Protein Metrics presented at the American Society for Mass Spectrometry describes the formation of NP protein coronas that enable analysis of subpopulations of the glycoproteome without the need for subsequent, glycopeptide-specific enrichment.
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Cloud scalable omics data analysis pipeline using serverless task infrastructure
This poster presented at the American Society for Mass Spectrometry describes the Proteograph™ Analysis Suite featuring multiple, integrated MS/MS database search engines including MaxQuant and DIA-NN, with automatic results generation, QC tools to evaluate data quality, and differential expression analysis for seamless generation of proteomics results.
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Mass spectrometry data acquisition with machine learning methods for deep plasma protein characterization
This poster describes an informed MS acquisition strategy improving sample-specific peptide/protein identification rates as well as reduced DDA stochasticity in repeated injections. The workflow leverages Seer’s current nanoparticles and generalized enrichment behaviors to inform MS instruments to increase orthogonality across panels maximizing ID rates.
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Deep Plasma Proteomics at Scale: A machine learning enhanced multi nanoparticle approach to improve the depth of plasma proteome coverage
Presented at the American Society for Mass Spectrometry, this poster highlights Proteograph™ platform performance comparison vs other mid-high throughout untargeted, label free plasma proteomics.
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Proteograph™ Analysis Suite: A cloud-scalable software suite for proteogenomics data analysis and visualization
This poster describes a cloud-scalable omics software supporting data analysis for the entire Proteograph Product Suite.
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Deep plasma proteomics studies at scale
Presented at the 2021 British Society for Proteome Research meeting, this poster provides an overview of Seer’s proprietary engineered nanoparticles that enable deep plasma proteomics studies at scale.
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Proteograph Product Suite used for unbiased and deep plasma proteome profiles
From ESHG 2021, this poster demonstrates that the Proteograph Product Suite can be used for unbiased and deep plasma proteome profiles that enable identification of protein variants in plasma at a scale sufficient to enable population-level proteomic studies.
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AACR: Identification of Differential Plasma Protein Isoforms in Early Lung Cancer
From AACR 2021, this poster demonstrates that measurements at the peptide level for the plasma proteome enable quantification of differential isoform abundance patterns using the Proteograph Product Suite.
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US HUPO: Deep plasma proteomics with trapped ion mobility and the Proteograph Product Suite
Proteograph Product Suite in combination with the timsTOF Pro provides a high-performance combination for rapid deep, precise, and accurate proteome profiling for biomarker discovery and biomedical research
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AGBT: Unbiased Plasma Proteomics in Lung Cancer, Alzheimer’s Disease and Proteogenomics
From AGBT 2021, a poster showing measurement of individual protein variants across the proteome, enabling unbiased proteogenomics at scale.
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