Through next generation sequencing (NGS), massively parallel sequencing has enabled high-throughput, scalable, and fast generation of genomic information from DNA and RNA (i.e., four bases: A, C, T, and G) to measure the human genome. While NGS has revealed important findings, proteomics must be considered to gain a comprehensive understanding of human biology.

For example, when we compare transcriptomic data with proteomic data in the same biosample, we see a low or modest correlation between. This relatively weak correlation between the transcriptome and the proteome supports the importance and added value of studying biology using proteins. Much like NGS enables the almost complete coverage of the genome, a next generation proteomics (NGP) technology that enables almost complete coverage of the proteome through unbiased and deep coverage will be an important advancement and milestone in understanding human biology.