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Maximize Genetic Discovery
Insights into pQTL and proteogenomics for advanced genetic research.
In the rapidly evolving field of genetics research, precise mapping of protein quantitative trait loci (pQTLs) has emerged as crucial to understanding underlying biology.
This webinar introduces the next frontier – merging proteogenomics with state-of-the-art techniques – to significantly elevate the precision and scope of pQTL studies.
You will gain insights into how the combination of Seer’s Proteograph® technology with mass-spectrometry techniques overcome traditional shortfalls and offer unprecedented depth in the study of protein functions and their genetic foundations.
Learning Objectives
- Weill Cornell Medicine – Qatar’s groundbreaking study quantifying over 18,000 unique peptides from ~3,000 proteins to identify protein-altering variants and variant peptides.
- Addressing challenges (i.e., target identity and non-specific binding issues) in high-throughput affinity proteomics.
- The identification and significance of protein-altering variants and variant peptides, refining pQTLs studies.
- Integrating proteomic data with genomics (GWAS) to traverse new dimensions in drug target prioritization and genetic discoveries.
- The high performance of Seer’s Proteograph workflow for precise mapping of pQTLs.
Featured Speakers
Karsten Suhre, Ph.D.
Professor of Biophysics & Physiology, Director of the Bioinformatics & Virtual Metabolomics Core, Weill Cornell Medicine - Qatar
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